This video shows you the simplest way to get rid of vocals from a song. You can use this process to remove vocals from any song (it may not work for some old songs). Adobe Audition is a audio editing software that allows you to do tons of modification. Central Channel Extractor is an effect that can help to make karaoke from a song by removing the original vocal.
However, there’s few limitations of removing vocal from a song which is, you can not remove the entire vocal there will a little left and the quality of the music will be damaged slightly. Adding will vocal will make it perfect. So don’t worry, just try it!